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Enantioselective ester hydrolysis catalyzed by β-cyclodextrin conjugated with β-hairpin peptides

✍ Scribed by Hiroshi Tsutsumi; Hiroshi Ikeda; Hisakazu Mihara; Akihiko Ueno


Book ID
108073170
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
177 KB
Volume
14
Category
Article
ISSN
0960-894X

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Diastereo- and Enantioselective Hydrogen
✍ Tsukuru Maeda; Dr. Kazuishi Makino; Masamichi Iwasaki; Prof. Yasumasa Hamada 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 371 KB

## Abstract The development of Ir‐catalyzed asymmetric hydrogenation of α‐amino‐β‐keto ester hydrochlorides is described. This reaction proceeds through a dynamic kinetic resolution to produce __anti__‐β‐hydroxy‐α‐amino acid esters in a high diastereo‐ and enantioselective manner. Mechanistic studi