Enantioselective hydrolysis of N-acylamino acid esters by L (or D)-histidine-attached β-cyclodextrins

Enantioselectively catalyzed hydrolysis

Enantioselectively catalyzed hydrolysis of p-nitrophenyl esters of N-protected L or D-amino acids by optically active hydroxamic acid and dipeptides

✍ Shuji Ono; Hideto Shosenji; Kimiho Yamada 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 218 KB

Catalyzed hydrolysis of p-nitrophenyl esters of N-protected L or D-phenylalanine by optically active hydroxamic acid or dipeptides in the presence of CTABr micelles showed high enantioselectivity (D/L=5.68 for L-ZLysZ(MHX)), demonstrating control of the direction of the enantioselectivity based on t