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Substrate Specificity of Maltose Phosphorylase

โœ Scribed by MORGAN, K.; WHELAN, W. J.

Book ID
109624618
Publisher
Nature Publishing Group
Year
1962
Tongue
English
Weight
238 KB
Volume
196
Category
Article
ISSN
0028-0836

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Species differences in substrate specifi
Species differences in substrate specificity of pyrimidine nucleoside phosphorylase
โœ Yoshihiko Maehara; Yoshihisa Sakaguchi; Tetsuya Kusumoto; Hiroki Kusumoto; Keizo ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 280 KB ๐Ÿ‘ 1 views

To compare the activity of pyrimidine nucleoside phosphorylase (PNP), an enzyme involved in the metabolism of 5-fluorouracil (5-FU), we used uridine (Urd), deoxyuridine (dUrd), and thymidine (dThd) as substrates and human, rat, and mouse neoplastic and normal tissues. As PNP activity was higher in t