✦ LIBER ✦

Study of the pharmacokinetic and pharmacogenetic contribution to the toxicity of high-dose methotrexate in children with acute lymphoblastic leukemia

✍ Scribed by Noha M. EL-Khodary, Sahar M. EL-Haggar, Manal A. Eid, Emad N. Ebeid

Book ID: 118821552
Publisher: Springer US
Year: 2011
Tongue: English
Weight: 301 KB
Volume: 29
Category: Article
ISSN: 1357-0560
DOI: 10.1007/s12032-011-9997-6

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacokinetics of high dose methotrexa

Pharmacokinetics of high dose methotrexate infusion in children with acute lymphoblastic leukemia during routine clinical monitoring

✍ M.B. Regazzi; R. Rondanelli; M. Molinaro; M. Aricò; F. Porta; L. Nespoli 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 239 KB

6-Mercaptopurine dosage and pharmacokine

6-Mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia

✍ Schmiegelow, K; Bretton-Meyer, U 📂 Article 📅 2001 🏛 Nature Publishing Group 🌐 English ⚖ 117 KB

Genetic polymorphisms of folate metaboli

Genetic polymorphisms of folate metabolic enzymes and toxicities of high dose methotrexate in children with acute lymphoblastic leukemia

✍ Samart Pakakasama; Kittima Kanchanakamhaeng; Saowanee Kajanachumpol; Umaporn Udo 📂 Article 📅 2007 🏛 Springer 🌐 English ⚖ 76 KB

Assessment of renal function during high

Assessment of renal function during high-dose methotrexate treatment in children with acute lymphoblastic leukemia

✍ Ylinen, Elisa; Jahnukainen, Kirsi; Saarinen-Pihkala, Ulla M.; Jahnukainen, Timo 📂 Article 📅 2014 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB

Palonosetron for the prevention of nause

Palonosetron for the prevention of nausea and vomiting in children with acute lymphoblastic leukemia treated with high dose methotrexate

✍ Sambavy Nadaraja; Aissata Diop Mamoudou; Harald Thomassen; Peder Skov Wehner; St 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB

Disposition of oral methotrexate in chil

Disposition of oral methotrexate in children with acute lymphoblastic leukemia and its relation to 6-mercaptopurine pharmacokinetics

✍ Koren, Gideon ;Solh, Hassan ;Klein, Julia ;Soldin, Stephen J. ;Greenberg, Mark 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 444 KB

We studied the disposition phannacokinetics of methotrexate (MTX) given orally to 16 children with acute lyrnphoblastic leukemia (ALL) and its relation to the pharrnacokinetics of 6-mercaptopurine (6MP) in the same children. There was an eightfold variability in area-under-concentration tirnecurve (