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Genetic polymorphisms of folate metabolic enzymes and toxicities of high dose methotrexate in children with acute lymphoblastic leukemia

✍ Scribed by Samart Pakakasama; Kittima Kanchanakamhaeng; Saowanee Kajanachumpol; Umaporn Udomsubpayakul; Nongnuch Sirachainan; Amnuay Thithapandha; Suradej Hongeng


Publisher
Springer
Year
2007
Tongue
English
Weight
76 KB
Volume
86
Category
Article
ISSN
0939-5555

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High-dose methotrexate (HDMTX, 1,000 mg/m2) and cranial irradiation/sequential chemotherapy (RTSC) were compared for ability to extend complete remission durations in children with acute lymphoblastic leukemia (ALL). Three hundred thirty patients were enrolled in the study, according to our criteria

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