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Pharmacokinetics of high dose methotrexate infusion in children with acute lymphoblastic leukemia during routine clinical monitoring

✍ Scribed by M.B. Regazzi; R. Rondanelli; M. Molinaro; M. Aricò; F. Porta; L. Nespoli


Book ID
115885674
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
239 KB
Volume
183
Category
Article
ISSN
0014-2999

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High-dose methotrexate improves clinical
✍ Abromowitch, Minnie ;Ochs, Judith ;Pui, Ching-Hon ;Kalwinsky, David ;Rivera, Gas 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 682 KB

High-dose methotrexate (HDMTX, 1,000 mg/m2) and cranial irradiation/sequential chemotherapy (RTSC) were compared for ability to extend complete remission durations in children with acute lymphoblastic leukemia (ALL). Three hundred thirty patients were enrolled in the study, according to our criteria