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Study of the mechanism of optical resolutions via diastereoisomeric salt formation

✍ Scribed by D. Kozma; Klára Tomor; C. Novák; G. Pokol; E. Fogassy


Publisher
Springer Netherlands
Year
1996
Tongue
English
Weight
460 KB
Volume
46
Category
Article
ISSN
0022-5215

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Several preparative resolutions of 5,5-disubstituted hydantoins have been achieved via fractional crystallization of diastereoisomeric salts. The process can be extended by making use of the difference between the variation of solubilities of the hydantoins and their salts with a-methylbenzylamine a