Preparative resolution of some 5,5-hydan
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Gérard Coquerel; Marie-Noëlle Petit; Roger Bouaziz; Dominique Depernet
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Article
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1992
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John Wiley and Sons
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English
⚖ 266 KB
Several preparative resolutions of 5,5-disubstituted hydantoins have been achieved via fractional crystallization of diastereoisomeric salts. The process can be extended by making use of the difference between the variation of solubilities of the hydantoins and their salts with a-methylbenzylamine a