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Study of a novel hypervariable region in hepatitis C virus (HCV) E2 envelope glycoprotein

✍ Scribed by Myriam Troesch; Isabelle Meunier; Pascal Lapierre; Normand Lapointe; Fernando Alvarez; Marc Boucher; Hugo Soudeyns

Book ID
113946908
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
354 KB
Volume
352
Category
Article
ISSN
0042-6822

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## Abstract The N‐terminal end of the hepatitis C virus (HCV) envelope glycoprotein E2 contains a stretch of 27 amino acids that exhibit increased variability. This hypervariable region 1 (HVR‐1), as it is normally referred to, is thought to contain epitopes that come under humoral immune attack. I