A concise synthesis of a precursor of dienyl cembranoids starting from geraniol is reported. All of the four chiral centers in the dienyl unit were established by Sharpless kinetic resolution, asymmetric epoxidation and dihydroxylation.
Studies toward the Total Synthesis of Sorangiolides and Their Analogues. A Convergent Stereoselective Synthesis of the Macrocyclic Lactone Precursors
β Scribed by Das, Sanjib; Abraham, Sunny; Sinha, Subhash C.
- Book ID
- 125542153
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 115 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1523-7060
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
AbJtract : A concise stereoselective route to the right hand fragment of solandelactones have been developed, where initial synthesis of the key bifunctional cyclopropane intermediate 2 was followed by construction of the eight-membered lactone ring in good overall yield.
An advanced ring-closing metathesis precursor for the synthesis of the marine macrolide neopeltolide is prepared in a stereocontrolled manner by the coupling of the C2-C10 and C11-C16 subunits. The metathesis reaction of 4 with Grubbs' II or Nolan's indenylidene catalyst led to the unexpected format