Studies Toward the Stereocontrolled Synthesis of a Key Azetidinone-Acid Intermediate in the Preparation of a New Carbapenem
β Scribed by Philippe Remuzon; Daniel Bouzard; Pierre DiCesare; Munir Essiz; Jean-Pierre Jacquet; Andrei Nicolau; Alain Martel; Marcel Menard; Carol Bachand
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 880 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
A short stereoselective synthesis of the acetoxy azetidinone (1), an important precursor of several biologically active β€-lactam antibiotics, has been accomplished in seven steps and 32.8% overall yield from the easily available and inexpensive (R) ethyl 3-hydroxybutanoate.
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