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Studies on the synthesis of the antitumour agent CC-1065. Synthesis of the cyclopropapyrroloindole portion

โœ Scribed by Magnus, Philip; Gallagher, Timothy


Book ID
121261699
Publisher
The Royal Society of Chemistry
Year
1984
Tongue
English
Weight
184 KB
Volume
6
Category
Article
ISSN
0022-4936

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Synthesis of the combined centre- and ri
โœ Richard E Bolton; Christopher J Moody; Charles W Rees; Gabriel Tojo ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 185 KB

The complete centre-and right-hand section of the anti-tumour antibiotic CC-1065, known -\_ as ?Di-I dimer (31, has been synthesised by coupling the pyrroloindole (6) and pyrroloindoline (51, followed by functional group transformations; the synthetic PDE-I dimer (3) was identical to material obtain