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Studies on the synthesis of the antitumor agent CC-1065. Synthesis of the unprotected cyclopropapyrroloindole A portion using the 3,3'-bipyrrole strategy

โœ Scribed by Magnus, Philip; Gallagher, Timothy; Schultz, James; Or, Yat Sun; Ananthanarayan, T. P.


Book ID
119949368
Publisher
American Chemical Society
Year
1987
Tongue
English
Weight
808 KB
Volume
109
Category
Article
ISSN
0002-7863

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Studies on the antitumor agent CC-1065 :
โœ Serge Halazy; Philip Magnus ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 184 KB

Sequential conjugate additions of methyl, TOSMIC anion and TOSMIC anion to I-pkenyZsuZfonyZ-1,3-butadiene provides a direct route to 3,3l-bipyrroles, andillustrates that I-pkenylsuZfonyZ-1,3-butadiene can functionas an electropkilic 1,3-butadiene equivalent. Recently we reported the synthesis of th