✦ LIBER ✦

Studies on the Synthesis of (2 S ,3 R )-3-Hydroxy-3-methylproline via C 2 −N Bond Formation

✍ Scribed by Shen, Jun-Wei; Qin, Dong-Guang; Zhang, Hong-Wang; Yao, Zhu-Jun

Book ID: 120446257
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 124 KB
Volume: 68
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo0349328

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthetic study of polyoxypeptin: stereo

Synthetic study of polyoxypeptin: stereoselective synthesis of (2S,3R)-3-hydroxy-3-methylproline

✍ Yasuo Noguchi; Hiromi Uchiro; Tatsuhiro Yamada; Susumu Kobayashi 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 72 KB

The first synthesis of (2S,3R)-3-hydroxy-3-methylproline, which is a novel amino acid of polyoxypeptin, a potent inducer of apoptosis in human pancreatic carcinoma AsPC-1, was accomplished. The key feature of the synthesis is the palladium-catalyzed intramolecular N-allylation of alkenyloxirane to t

Synthetic studies on polyoxypeptins: ste

Synthetic studies on polyoxypeptins: stereoselective synthesis of (2S,3R)-3-hydroxy-3-methylproline using SmI2-mediated cyclization

✍ Kazuishi Makino; Ai Kondoh; Yasumasa Hamada 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 75 KB

Stereoselective synthesis of (2S,3R)-3-hydroxy-3-methylproline (3), a component of polyoxypeptins, has been achieved by use of SmI 2 -mediated diastereoselective cyclization reaction as a key step.

Enantioselective Synthesis of (2 S ,3 R

Enantioselective Synthesis of (2 S ,3 R )-3-Hydroxy-3-methylproline, A Novel Amino Acid Found in Polyoxypeptins

✍ Qin, Dong-Guang; Zha, Hui-Yan; Yao, Zhu-Jun 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 49 KB

Asymmetric Synthesis of α-Amino 1,3-Dith

Asymmetric Synthesis of α-Amino 1,3-Dithioketals from Sulfinimines (N-Sulfinyl Imines). Synthesis of (2S,3R)-(−)-3-Hydroxy-3-methylproline

✍ Davis, Franklin A.; Ramachandar, Tokala; Liu, Hu 📂 Article 📅 2004 🏛 American Chemical Society 🌐 English ⚖ 56 KB

Asymmetric Synthesis of α-Amino 1,3-Dith

Asymmetric Synthesis of α-Amino 1,3-Dithioketals from Sulfinimines (N-Sulfinyl Imines). Synthesis of (2S,3R)-(-)-3-Hydroxy-3-methylproline.

✍ Franklin A. Davis; Tokala Ramachandar; Hu Liu 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 195 KB 👁 1 views

Stereocontrolled synthesis of (2S *,3R*,

Stereocontrolled synthesis of (2S *,3R*,4R*)-4-hydroxy-3-methylproline using a silicon assisted aza-[2,3]-Wittig sigmatropic rearrangement

✍ Anderson, James C.; Flaherty, Alice 📂 Article 📅 2001 🏛 Royal Society of Chemistry ⚖ 88 KB