𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Studies on the synthesis of 16α-[18F]fluoroestradiol

✍ Scribed by Johannes Römer; Jörg Steinbach; Helmut Kasch


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
449 KB
Volume
47
Category
Article
ISSN
0969-8043

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Simultaneous preparation of 16α-[18F]flu
✍ J. Römer; F. Füchtner; J. Steinbach; H. Kasch 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 119 KB

## Abstract After successfully synthesizing 16__α__‐[^18^F]fluoroestradiol‐3,17__β__‐disulphamate in an automatic procedure, we studied the conditions for obtaining 16__α__‐[^18^F]fluoroestradiol‐monosulphamates in a similar manner. The described procedure can simultaneously provide approximately 3

Simplified and automatic one-pot synthes
✍ K. E. Knott; D. Grätz; S. Hübner; S. Jüttler; C. Zankl; M. Müller 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 256 KB

16α‐[^18^F]Fluoroestradiol (16α‐[^18^F]FES, 1) is known as a valuable tracer in molecular imaging as estrogen receptor (ER) ligand for investigation of primary and metastatic breast cancer. ER concentration in human breast tumor cells is a significant indicator for the degree of disease and is often

NCA 16α-[18F]fluoroestradiol-17β: The ef
✍ James W. Brodack; Michael R. Kilbourn; Michael J. Welch; John A. Katzenellenboge 📂 Article 📅 1986 🏛 Elsevier Science ⚖ 500 KB

Although the reported synthesis of the title compound resulted in a high radiochemical yield (43% based on resolubilized 18F), the effective specific activity at EOS was low (166 Ci/mmol). Reduction in the amount of carrier fluoride in the target water improved the effective specific activity of the