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Studies on the stability of 3H-dopamine in neostriatal membrane preparations: Effects of ascorbic acid

โœ Scribed by Richard E. Heikkila; Felicitas S. Cabbat

Book ID
118941755
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
365 KB
Volume
32
Category
Article
ISSN
0024-3205

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โœ Dr. H. Sershen; E. A. Debler; A. Lajtha ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 393 KB

The effects of ascorbic acid on the synaptosomal uptake of r3H]MPP+, [3H]dopamine, and [I4C]GABA were examined in attempts to understand the mechanism of ascorbic acid attenuation of MPTP neurotoxicity. [3HJDopamine uptake was increased at lower levels (0.01 and 0.1 mM) and decreased at higher level