Three invited international experts present overviews of recent developments in key fields and will submit chapters for the book. Jane Hurst from Liverpool University in the UK presents an overview on the function, mechanisms and evolution of chemical signals, Penelope Hawkins from the University o
Studies on the receptors to 5α-androst-16-en-3-one and 5α-androst-16-en-3α-ol in sow nasal mucosa
✍ Scribed by Gennings, J.N.; Gower, D.B.; Bannister, L.H.
- Book ID
- 123315715
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 614 KB
- Volume
- 496
- Category
- Article
- ISSN
- 0304-4165
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📜 SIMILAR VOLUMES
P r e v i o u s l y , we had s u c e s s f u l l y s y n t h e s i z e d [ 5a. 6a-HIandrost-16-en-3-one (3) from 3B-acetoxy-androst-5-en-17-0ne (1) i n f i v e s t e p s 121. After c a t a l y t i c hydrogenation of t h e 5-double bond of (1) w i t h T2 t h e corresponding 17-tosylhydrazone had to
The synthesis of [5α, 6α‐^3^H]‐5α‐androst‐16‐en‐3‐one, starting with the catalytic tritiation of 3β‐acetoxy‐androst‐5‐en‐17‐one, is described. The so‐called “boar taint ketone” was obtained with high specific activity (21 Ci/mmol) and radiochemical purity better than 98 %.
## Abstract An efficient one step synthesis of [3__α__‐^3^H]5__α__‐androst‐16‐en‐3__β__‐ol by NaBT~4~ reduction of a ketone precursor is described. The specific activity of the product was 21.6 Ci/mmol with a radiochemical purity >99%. Synthesis of the precursor, 5__α__‐androst‐16‐en‐3‐one, from co