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Studies on the reactivity of bicyclomycin with nucleophilic amino acid derivatives

โœ Scribed by Abuzar, Syed; Kohn, Harold


Book ID
126057227
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
532 KB
Volume
54
Category
Article
ISSN
0022-3263

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Syntheses of a-fluoro-o-amino acid derivatives have been attempted from the viewpoints of their structural and biological interests. o-Amino esters were diazotised with i-AmONO or NaN02 to produce the corresponding diazo esters, which were treated with NBS and HF/pyridine to yield the a-bromo-a-fluo