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Studies on the Chemistry of ThienoannelatedO,N- andS,N-Containing Heterocycles, 28 [1]. Synthesis of Imidazo[1,5-d]thieno[2,3-b][1,4]thiazine Derivatives asGABA-Receptor Ligands

✍ Scribed by Thomas Erker; Karin Trinkl


Book ID
106213188
Publisher
Springer Vienna
Year
2003
Tongue
English
Weight
81 KB
Volume
134
Category
Article
ISSN
0026-9247

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Studies on the chemistry of thienoannela
✍ Thomas Erker; Norbert Handler πŸ“‚ Article πŸ“… 2002 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 38 KB πŸ‘ 1 views

## Abstract A facile synthesis of the imidazo[1,5‐__d__]thieno[2,3‐__b__][1,4]thiazine ring system is described. Reaction of 6‐benzyl‐2,3‐dihydro‐1__H__‐thieno[2,3‐__b__][1,4]thiazine‐2‐one (**1**) with potassium __tert__‐butoxide and diethylchlorophosphate gave intermediate **2** which resulted in

Studies on the chemistry of thienoannela
✍ Maria E. Schreder; Thomas Erker πŸ“‚ Article πŸ“… 2000 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 373 KB

## Abstract A new series of substituted thieno[1,4]thiazines with an urea moiety has been designed. The synthesis and results of replacement of the quinoline and indoline moieties of lead structure **1** are described. The key step in preparation was the substitution with 4‐nitrophenyl chloroformat