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Studies on the biochemical pharmacology of 5-IODO-2'-deoxycytidine in vitro and in vivo

โœ Scribed by John W. Cramer; William H. Prusoff; Arnold D. Welch; Alan C. Sartorelli; Irvine W. Delamore; Carl F. Von Essen; Pauline K. Chang


Book ID
115768232
Publisher
Elsevier Science
Year
1962
Tongue
English
Weight
643 KB
Volume
11
Category
Article
ISSN
0006-2952

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## Abstract __cis__โ€Dichlorodiammineplatinum and 5โ€azaโ€2โ€ฒโ€deoxycytidine display a considerable synergistic effect in L1210 and La mouse leukemia __in vivo__; the combination of both drugs is also clearly synergistic __in vitro__as evidenced by the effects on cell growth and cell survival in softโ€ag