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Studies on ring opening reactions of β-lactams

✍ Scribed by Susanne Pippich; Herbert Bartsch; Wolfgang Holzer

Book ID
108378661
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
352 KB
Volume
53
Category
Article
ISSN
0040-4020

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## Abstract A variety of hydroxy epoxides have been obtained from well defined hydroxy‐alkenyl derivatives. Their subsequent intramolecular ring‐opening allowed unprecedented classes of spiro‐lactams to be obtained. The effect of the epoxide stereochemistry and of the reaction temperature on the re