𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Dihydrobenzopyran skeleton from β-lactams: a stereoselective ring opening–ring closure reaction sequence

✍ Scribed by Paola Del Buttero; Giorgio Molteni; Antonio Papagni; Tullio Pilati


Book ID
108283888
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
170 KB
Volume
16
Category
Article
ISSN
0957-4166

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


From aziridines to carbapenems via a nov
✍ David Tanner; Peter Somfai 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 431 KB

An enantioselective synthesis of the carbapenem antibiotic (+)-ps-5 is described. The starting point is the chiral Sharpless epoxyalcohol 2 which is transformed stereospecifically to the eziridine 6. Regioeelective ring-ope&ng of 6 by'LiEt Cu followed by RuQ oxidation yields the @-sulfonamide cat-bo