## Abstract A variety of hydroxy epoxides have been obtained from well defined hydroxy‐alkenyl derivatives. Their subsequent intramolecular ring‐opening allowed unprecedented classes of spiro‐lactams to be obtained. The effect of the epoxide stereochemistry and of the reaction temperature on the re
✦ LIBER ✦
Synthesis of Four-Membered Ring Spiro-β-lactams by Epoxide Ring-Opening.
✍ Scribed by Fides Benfatti; Giuliana Cardillo; Luca Gentilucci; Alessandra Tolomelli
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 50 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Efficient methods to prepare β,γ‐disubstituted γ‐lactams with syn and anti configuration are reported.