Insulin can replace the factor(s) in calf serum whose amount is limiting for multiplication in cell culture of chicken embryo fibroblasts and of chicken embryo fibroblasts infected and converted by avian sarcoma virus. In serum-free, insulincontaining medium, converted cells multiply more than do un
Studies on carcinogenesis by avian sarcoma viruses: VIII. Glycolysis and cell multiplication
โ Scribed by Howard M. Temin
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- French
- Weight
- 608 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0020-7136
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โฆ Synopsis
Glycolysis and multiplication were studied in parallel cultures of uninfected and of avian sarcoma virus-converted chicken and duck cells. It was found that:
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The increased multiplication of converted chicken cells in the presence of limited amounts of serum results from more efficient utilization of multiplicationstimulating activity rather than increased binding or uptake of this activity. X lo5 cells in 60-mm plastic petri dishes (Falcon Plastics) wer