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Studies of the Mechanisms of Adduction of 2‘-Deoxyadenosine with Styrene Oxide and Polycyclic Aromatic Hydrocarbon Dihydrodiol Epoxides

✍ Scribed by Kim, Hye-Young H.; Finneman, Jari I.; Harris, Constance M.; Harris, Thomas M.


Book ID
126844309
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
329 KB
Volume
13
Category
Article
ISSN
0893-228X

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Synthesis and sepamtion of the diastereomeric tram Nz-2'deoxyguanosine edducts of tetrehydrophenanthtae 3,4-epoxide end beauo[a]pyrene 7,8diol9, IO-epoxide (knzylic hydroxyl group end epoxide oxygen tmns), as well es the incaporation of the former into the pentanucleotide TpA#pApT, am described.