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Epoxide and diol epoxide adducts of polycyclic aromatic hydrocarbons at the exocyclic amino group of deoxyguanosine

✍ Scribed by Barbara Zajc; Mahesh K. Lakshman; Jane M. Sayer; Donald M. Jerina

Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
321 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis

Synthesis and sepamtion of the diastereomeric tram Nz-2'deoxyguanosine edducts of tetrehydrophenanthtae 3,4-epoxide end beauo[a]pyrene 7,8diol9, IO-epoxide (knzylic hydroxyl group end epoxide oxygen tmns), as well es the incaporation of the former into the pentanucleotide TpA#pApT, am described.

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