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Metabolites of polycyclic aromatic hydrocarbons. II. Synthesis of 7,8-dihydrobenzo[a]pyrene-7,8-diol and 7,8-dihydrobenzo[a]pyrene-7,8-epoxide

✍ Scribed by Daniel J. McCaustland; James F. Engel

Publisher
Elsevier Science
Year
1975
Tongue
French
Weight
206 KB
Volume
16
Category
Article
ISSN
0040-4039

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Labeled metabolites of polycyclic aromat
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✍ Daniel J. McCaustland; W. P. Duncan; James F. Engel 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 245 KB

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The concept of stereoselectivity during monooxygenase catalyzed addition of an oxygen atom to the stereoheterotopic faces of a polycyclic aromatic hydrocarbon (PAH) was initially proposed' on the basis of (a) liver microsomal metabolism studies on naphthalene and (+)-naphthalene 1,2-oxide and (b) sy