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Labeled metabolites of polycyclic aromatic hydrocarbons II. 4,5-dihydrobenzo[a]pyrene-4,5-epoxide-G-3H via cis 4,5-dihydrobenzo[a]pyrene-4,5-diol-G-3H

✍ Scribed by Kenneth C. Kolwyck; W. P. Duncan; James F. Engel; James K. Selkirk


Publisher
John Wiley and Sons
Year
1976
Tongue
French
Weight
223 KB
Volume
12
Category
Article
ISSN
0022-2135

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✦ Synopsis


Recent i n v e s t i g a t i o n s concerning t h e o x i d a t i v e metabolism of b e n z o k lpyrene (Be) have implicated various epoxides as intermediates [l].


📜 SIMILAR VOLUMES


Labeled metabolites of polycyclic aromat
✍ Daniel J. McCaustland; Daniel L. Fischer; W. P. Duncan; Edward J. Ogilvie; James 📂 Article 📅 1976 🏛 John Wiley and Sons 🌐 French ⚖ 294 KB

## Abstract The syntheses of trans‐7,8‐dihydrobenzo[a]pyrene‐7,8‐diol‐G‐^3^H (V) and (±)‐7α, 8β‐dihydroxy‐9β,10β‐epoxy‐7,8,9,10‐tetrahydrobenzo[a]pyrene‐G‐^3^H (VI) are described. The specific activities of V and VI were 158 mCi/mmole and 220 mCi/mmole, respectively. The key intermediate, trans‐7,8