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Studies of human transcortin at different pHs: Circular dichroism, polymerisation and binding affinity

โœ Scribed by F. Le Gaillard; J.P. Aubert; M. Dautrevaux; M.H. Loucheux-Lefebvre


Book ID
115906393
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
537 KB
Volume
64
Category
Article
ISSN
0014-5793

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The reversible binding of ethacrynic acid was characterized by a difference circular dichroism method. A 2/1 stoichiometry was determined for the [drug]/[HSA] (human serum albumin) complex. The reversible binding of ethacrynic acid to HSA determines direct competition with ligands that selectivity b