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Studies in macrolide synthesis: Stereocontrolled synthesis of a C1C13 segment of concanamycin A

✍ Scribed by Ian Paterson; Malcolm D. McLeod

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
329 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

The Ct-Ct3 segment 6 of concanamycin A (1) was prepared by a highly stereocontrolled route (87% overall ds) in 16 steps from the ester 9. Key steps are the one-pot aldol/reduction, 8 + 12, and the HWB reaction, 18 + 19 + 6.8 1997 Elsevier Science Ltd.

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