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Structures of the extracellular domain of the type I tumor necrosis factor receptor

✍ Scribed by James H Naismith; Tracey Q Devine; Tadahiko Kohno; Stephen R Sprang


Book ID
114329427
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
404 KB
Volume
4
Category
Article
ISSN
0969-2126

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We evaluated the effect of UV-B light at 302 nm on a model therapeutic protein, 2.6 D type I soluble tumor necrosis factor receptor (sTNF-RI). This protein contains a single Trp at position 97 and seven native disulfide bonds along its interior from the N to the C-terminus. At a protein concentratio