Structures of modified cardenolides. II. (20R)-3β-Hydroxy-22-methylene-5β-card-14-enoline
✍ Scribed by Rohrer, D. C. ;Duax, W. L. ;Fullerton, D. S.
- Book ID
- 117860093
- Publisher
- International Union of Crystallography
- Year
- 1976
- Weight
- 345 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0567-7408
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📜 SIMILAR VOLUMES
The synthesis of a 30-thiocyanatocardenolide is described. The compound exhibited about 0.1 times the cardiotonic effect of digitoxigenin in the isolated frog heart preparation. A t a dosage of 20 mg/kg in the intact rat, it elicited ECG changes similar to those seen with a 10-mghg dose of digitoxig
Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.009 A Ê Disorder in solvent or counterion R factor = 0.077 wR factor = 0.227 Data-to-parameter ratio = 15.7 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.