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Structures of Mismatch Replication Errors Observed in a DNA Polymerase

โœ Scribed by Sean J. Johnson; Lorena S. Beese

Book ID
117269859
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
569 KB
Volume
116
Category
Article
ISSN
0092-8674

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## Abstract The primary role of mismatch repair (MMR) is to maintain genomic stability by removing replication errors from DNA. This repair pathway was originally implicated in human cancer through an association between microsatellite instability in colorectal tumors in hereditary nonpolyposis col