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Evidence for Preferential Mismatch Repair of Lagging Strand DNA Replication Errors in Yeast

โœ Scribed by Youri I. Pavlov; Ibrahim M. Mian; Thomas A. Kunkel

Book ID
114319851
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
148 KB
Volume
13
Category
Article
ISSN
0960-9822

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## Abstract The primary role of mismatch repair (MMR) is to maintain genomic stability by removing replication errors from DNA. This repair pathway was originally implicated in human cancer through an association between microsatellite instability in colorectal tumors in hereditary nonpolyposis col