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Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

✍ Scribed by Strand, Micheline; Prolla, Tomas A.; Liskay, R. Michael; Petes, Thomas D.


Book ID
109785295
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
456 KB
Volume
365
Category
Article
ISSN
0028-0836

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The efficiency and direction of mismatch correction in the Saccharomyces cerevisiae SUP4-o gene were not altered by an excision-repair defect (rad1). Although excision-repair functions remove methylated adenine from yeast, adenine methylation at a GAC sequence in SUP4-o did not direct the correction