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Structures of Furanovibsanins A—G from Viburnum awabuki.

✍ Scribed by Yoshiyasu Fukuyama; Miwa Kubo; Takako Fujii; Asami Matsuo; Yuka Minoshima; Hiroyuki Minami; Mai Morisaki


Book ID
101946636
Publisher
John Wiley and Sons
Year
2003
Weight
147 KB
Volume
34
Category
Article
ISSN
0931-7597

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Neovibsanines A and B, unprecedented dit
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Neovibsanines A and B, isolated from the leaves of Viburnum awabuki, are unprecedented tricyclic diterpenoids, which are presumably biosynthesized via consecutive ring cleavage and cyclization from vibsanine B. Their relative structures have been established by extensive analysis of spectroscopic da

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Spirovibsanin A, isolated from Viburnum awabuki, has been demonstrated to be an unprecedented vibsane-type 18-norditerpene consisting of a unique bicyclo[3.3.1] nonanespiro-g-lactone framework by a combination of 2D NMR data and conformational analysis using MacroModel.

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A unique neovibsane-type diterpene, neovibsanin C (1), isolated from the leaves of Viburnum awabuki, has been demonstrated to have an unprecedented structure macrocyclized via an endo-peroxide by extensive analyses of spectral data and chemical degradation as well as synthesis of I from neovibsanin