Structure−Activity Studies on a Series of a 2-Aminopyrimidine-Containing Histamine H 4 Receptor Ligands
✍ Scribed by Altenbach, Robert J.; Adair, Ronald M.; Bettencourt, Brian M.; Black, Lawrence A.; Fix-Stenzel, Shannon R.; Gopalakrishnan, Sujatha M.; Hsieh, Gin C.; Liu, Huaqing; Marsh, Kennan C.; McPherson, Michael J.; Milicic, Ivan; Miller, Thomas R.; Vortherms, Timothy A.; Warrior, Usha; Wetter, Jill M.; Wishart, Neil; Witte, David G.; Honore, Prisca; Esbenshade, Timothy A.; Hancock, Arthur A.; Brioni, Jorge D.; Cowart, Marlon D.
- Book ID
- 118168957
- Publisher
- American Chemical Society
- Year
- 2008
- Tongue
- English
- Weight
- 291 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A series of 2-heteroaryl-4-arylimidazoles with potent in vitro activity at the NPY5 receptor was developed. Introduction of electron-withdrawing groups on the 4-aryl ring led to a significant improvement of in vitro potency. Several analogues from this series had anorectic activity in rodent feeding