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Structure–Activity Relationship Analysis of the Peptide Deformylase Inhibitor 5-Bromo-1H-indole-3-acetohydroxamic Acid

✍ Scribed by Sylvain Petit; Yann Duroc; Valéry Larue; Carmela Giglione; Carole Léon; Coralie Soulama; Alexis Denis; Frédéric Dardel; Thierry Meinnel; Isabelle Artaud

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
678 KB
Volume
4
Category
Article
ISSN
1860-7179

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## Abstract **The cover picture shows** a “reverse” indole derivative in complex with __Bacillus stearothermophilus__ peptide deformylase (PDF). This compound was selected from a structure–activity relationship study as a potent inhibitor of bacterial PDFs and shows antibacterial activity toward __

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