𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Structure of Brefeldin A

✍ Scribed by H. P. Weber; D. Hauser; H. P. Sigg

Publisher
John Wiley and Sons
Year
1971
Tongue
German
Weight
218 KB
Volume
54
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

On the basis of X‐ray crystal structure analysis, CD. measurements, and asymmetric synthesis the absolute configuration of brefeldin A has been determined.

πŸ“œ SIMILAR VOLUMES

Stochastic conformational search of bref
Stochastic conformational search of brefeldin A and experimental structures
✍ Mark Froimowitz; Douglas J. Gordon; Adel Moussa; Reem M. Haidar; Clifford George πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 83 KB πŸ‘ 1 views

The macrocyclic lactone brefeldin A was used as a test molecule for the MM3-92 Stochastic Search conformational searching algorithm. A number of low energy conformers were found and 12 of these were also subjected to ab initio energy minimization using the 3-21G\* and 6-31G\* basis sets with the Spa

Total Synthesis of (+)-Brefeldin C, (+)-
Total Synthesis of (+)-Brefeldin C, (+)-nor-Me Brefeldin A and (+)-4-epi-nor-Me Brefeldin A
✍ Sylvie Archambaud; FrΓ©dΓ©ric Legrand; Karine Aphecetche-Julienne; Sylvain Collet; πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 582 KB

## Abstract A total synthesis of (+)‐brefeldin C (BFC) and two brefeldin A (BFA) analogues – (+)‐nor‐Me BFA and (+)‐4‐__epi__‐nor‐Me BFA – has been developed. Key features of the syntheses include desymmetrization of __meso__ anhydrides, a Carreira reaction to control the absolute configuration at

Total Synthesis of (+)-Brefeldin A.
Total Synthesis of (+)-Brefeldin A.
✍ Young-Ger Suh; Jae-Kyung Jung; Seung-Yong Seo; Kyung-Hoon Min; Dong-Yun Shin; Yo πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 34 KB πŸ‘ 2 views
NMR structure determination of brefeldin
NMR structure determination of brefeldin-A, a 13-membered ring fungal metabolite
✍ Robert Glaser; Dror Shiftan; Mark Froimowitz πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 96 KB πŸ‘ 1 views

Dissolution of brefeldin-A in CDCl 3 afforded two species in the ratio 13 : 1. Vicinal proton-proton coupling constants and NOE intensity enhancement measurements showed that the 13-membered ring conformation found by x-ray crystallography in the solid state appears to be preferred also in the solut