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Structure of blasticidin A

✍ Scribed by Shohei Sakuda; Makoto Ono; Hiroyuki Ikeda; Yasuhito Inagaki; Jiro Nakayama; Akinori Suzuki; Akira Isogai


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
226 KB
Volume
38
Category
Article
ISSN
0040-4039

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In previous papers"', we have reported the isolation and characterization of a new nucleoside designated cytosinine from the hydrolysis products of blasticidin.S, a useful antibiotic against rice blast desease. We wish to present the details leading to the assignment of structure I to cytosinine. Cy

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Blasticidin S is an antibiotic produced by Streotomyces -gi\_seochromogene\_s\_' and the structure has been established as shown in FIG. 1: It consists of a pyrimidine nucleoside and P-amino acid named cytosinine and blastidic acid, respectively. Hitherto, several reports had been published on the

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