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Structure of a nucleoside analogue, 3'-deoxy-2'-fluorothymidine

✍ Scribed by Everaert, D. H. ;Peeters, O. M. ;Blaton, N. M. ;De Ranter, C. J. ;Van Aerschot, A. ;Herdewijn, P.


Book ID
114507511
Publisher
International Union of Crystallography
Year
1990
Tongue
English
Weight
329 KB
Volume
46
Category
Article
ISSN
0108-2701

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6-Amino-3-(Ξ²-d-2-deΒ­oxy-erythro-furanosΒ­
✍ Sun, Zhenhua ;Lo, Wayne ;McLaughlin, Larry W. πŸ“‚ Article πŸ“… 2006 πŸ› International Union of Crystallography 🌐 English βš– 302 KB

The title compound [systematic name: (2__R__,3__R__,5__R__)-5-(6-amino-2-fluoropyridin-3-yl)-2-(hydroxymethyl)-2,3,4,5-tetrahydrofuran-3-ol], C~10~H~13~FN~2~O~3~, is a C-nucleoside with fluorine replacing the O2 carbonyl of deoxycytidine (dC). The furanose ring adopts a C2β€²-__endo__ conformation, wh