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Nucleosides. XVIII. Synthesis of 2'-Fluorothymidine, 2'-Fluorodeoxyuridine, and Other 2'-Halogeno-2'-Deoxy Nucleosides 1,2

✍ Scribed by Codington, John F.; Doerr, Iris L.; Fox, Jack J.


Book ID
126172916
Publisher
American Chemical Society
Year
1964
Tongue
English
Weight
980 KB
Volume
29
Category
Article
ISSN
0022-3263

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Synthesis of (2β€²S)-2β€²-Deoxy-2β€²-C-methylp
✍ Gerardo Caballero; Mariana Gallo; Javierβ€…M. Montserrat; Adolfoβ€…M. Iribarren πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 German βš– 154 KB πŸ‘ 2 views

We describe the stereoselective synthesis of (2'S)-2'-deoxy-2'-C-methyladenosine ( ) and (2'S)-2'-deoxy-2'-C-methylinosine ( ) as well as their corresponding cyanoethyl phosphoramidites 16 and 19 from 6-O-(2,6dichlorophenyl)inosine as starting material. The methyl group at the 2'-position was introd