Nucleosides. XIX. Structure of the 2'-Halogeno-2'-Deoxypyrimidine Nucleosides 1
โ Scribed by Codington, John F.; Doerr, Iris L.; Fox, Jack J.
- Book ID
- 126062816
- Publisher
- American Chemical Society
- Year
- 1964
- Tongue
- English
- Weight
- 815 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
Al~tract: A pyrimidine moiety was tethered at the 3'-~-position of D-threo-furanosides. By carefully controlling the reaction conditions, pyrimidine bases can be delivered to the anomeric center to give of ~-pyrimidine nucleosides in good yield and with complete stereocontrol.
Stereocontrolled Synthesis of ฮฒ-2'-Deoxypyrimidine Nucleosides via Intramolecular Glycosylations. -In continuation of efforts to develop general methods for the exclusive formation of ฮฒ-nucleosides, the base-promoted reaction of the pentafuranoside (II) with allyloxypyrimidines (II) is reported. Af
Sugar-peracetylated 1-(b-d-glucopyranosyl)-, 1-(b-d-galactopyranosyl)-, and 1-(b-d-xylopyranosyl)-6-aryl-5-cyano-2-thiouracils 2ยฑ4 and the corresponding 1-pyranosyl-2-(pyranosylthio)pyrimidines 5ยฑ7 undergo ecient ammonolysis (NH 3 /MeOH, 0323 C, 16 h) to give the corresponding 1-(b-d-pyranosyl)-6-ar