Determination of the N-acetyl metabolite
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John Cocker; Alan R. Boobis; Donald S. Davies
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Article
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1988
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John Wiley and Sons
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English
⚖ 569 KB
A sensitive and specific gas chromatographic/mass spectrometric assay is described for the determination of Nacetyl 4,4'-methylene dianiline (N-acetyl MDA) and N-acetyl 4,4'-methylene-bis(2-chloroaniline) (N-acetyl MbOCA) in urine. The method is based on the solvent extraction of the compounds toget