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High-performance liquid chromatographic determination of the 1,4-diketo and 1,4-diketo-2,3-dihydroxy metabolites of lonapalene in rat urine

โœ Scribed by Chih-Hen Kiang; Carol Lee


Publisher
Elsevier Science
Year
1991
Weight
551 KB
Volume
565
Category
Article
ISSN
0378-4347

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High-performance liquid chromatographic
โœ Junichi Ishida; Masatoshi Yamaguchi; Masaru Nakamura ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 377 KB

A high-performance liquid chromatographic method for the fluorometric determination of 1,2,3,4-tetrahydroisoquinoline in rat brain is described. 1,2,3,4-Tetrahydroisoquinoline and 4-phenylpiperidine (internal standard) are isolated by liquid-liquid extraction, and then converted into the correspondi