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High-performance liquid chromatographic determination of 1,2-diethyl-3-hydroxypyridin-4-one and its 2-(1-hydroxyethyl) metabolite in rat blood

✍ Scribed by R.O. Epemolu; S. Singh; R.C. Hider; L.A. Damani

Publisher
Elsevier Science
Year
1992
Weight
302 KB
Volume
573
Category
Article
ISSN
0378-4347

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A high-performance liquid chromatographic method for the fluorometric determination of 1,2,3,4-tetrahydroisoquinoline in rat brain is described. 1,2,3,4-Tetrahydroisoquinoline and 4-phenylpiperidine (internal standard) are isolated by liquid-liquid extraction, and then converted into the correspondi