✦ LIBER ✦

Structure-based drug design of chromone antagonists of the adenosine A2A receptor

✍ Scribed by Andrews, Stephen P.; Mason, Jonathan S.; Hurrell, Edward; Congreve, Miles

Book ID: 121479436
Publisher: The Royal Society of Chemistry
Year: 2014
Tongue: English
Weight: 460 KB
Volume: 5
Category: Article
ISSN: 2040-2503
DOI: 10.1039/C3MD00338H

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Molecular docking study of A3 adenosine

Molecular docking study of A3 adenosine receptor antagonists and pharmacophore-based drug design

✍ Jing Wei; Hui Li; Wanlu Qu; Qingzhi Gao 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 611 KB

The Discovery and Synthesis of Novel Ade

The Discovery and Synthesis of Novel Adenosine Receptor (A2A) Antagonists.

✍ Julius J. Matasi; John P. Caldwell; Jinsong Hao; Bernard Neustadt; Leyla Arik; C 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 21 KB 👁 2 views

Highlights on the Development of A2A Ade

Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists

✍ Gloria Cristalli; Barbara Cacciari; Diego Dal Ben; Catia Lambertucci; Stefano Mo 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 1014 KB

Highlights on the Development of A2A Ade

Highlights on the Development of A2A Adenosine Receptor Agonists and Antagonists

✍ Gloria Cristalli; Barbara Cacciari; Diego Dal Ben; Catia Lambertucci; Stefano Mo 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 11 KB 👁 1 views

Metabolites of the Pyrimidine Amine Prel

Metabolites of the Pyrimidine Amine Preladenant as Adenosine A2a Receptor Antagonists

✍ Rosse, Gerard 📂 Article 📅 2012 🏛 American Chemical Society 🌐 English ⚖ 230 KB

Discovery of 2-aminoimidazopyridine aden

Discovery of 2-aminoimidazopyridine adenosine A2A receptor antagonists

✍ Brian F. McGuinness; Andrew G. Cole; Guizhen Dong; Marc-Raleigh Brescia; Yuefei 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 813 KB

A novel series of adenosine A(2A) receptor antagonists was identified by high-throughput screening of an encoded combinatorial compound collection. The initial hits were optimized for A(2A) binding affinity, A(1) selectivity, and in vitro microsomal stability generating orally available 2-aminoimida