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Structure and in vivo function of Hsp90

✍ Scribed by Laurence H Pearl; Chrisostomos Prodromou


Book ID
114314840
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
366 KB
Volume
10
Category
Article
ISSN
0959-440X

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## Abstract __The molecular chaperone Hsp90 is responsible for activation and stabilization of several oncoproteins in cancer cells, and has emerged as an important target in cancer treatment because of this pivotal role. In recent years, interests have arisen around structure‐based design of small