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A global view of Hsp90 functions

✍ Scribed by Chiosis, Gabriela; Dickey, Chad A; Johnson, Jill L

Book ID: 118216645
Publisher: Nature Publishing Group
Year: 2013
Tongue: English
Weight: 370 KB
Volume: 20
Category: Article
ISSN: 1545-9993
DOI: 10.1038/nsmb.2481

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In a recent paper, Rutherford and Lindquist (1998. Nature 396:336-342) identified mutations in the Hsp90 protein that act to unmask hidden genetic variation with a variety of phenotypic effects. The Hsp90 protein has a number of properties that suggest a role in regulating the expression of genetic