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Structure and function of γ-secretase complex

✍ Scribed by Taisuke Tomita


Book ID
116775499
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
78 KB
Volume
58
Category
Article
ISSN
0168-0102

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## Abstract γ‐Secretase catalyzes intramembrane proteolysis of various type I membrane proteins, including the amyloid‐β precursor protein and the Notch receptor. Despite its importance in the pathogenesis of Alzheimer's disease and to normal development, this protease has eluded identification unt