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Structure and Function of the Pre-mRNA Splicing Machine

✍ Scribed by Joseph Sperling; Maia Azubel; Ruth Sperling


Book ID
113918877
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
587 KB
Volume
16
Category
Article
ISSN
0969-2126

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Nuclear pre-mRNAs must be precisely processed to give rise to mature cytoplasmic mRNAs. This maturation process, known as splicing, involves excision of intron sequences and ligation of the exon sequences. One of the major problems in understanding this process is how splice sites, the sequences whi